IGF-1 Human — 1 mg

Human IGF-1, also called insulin-like growth factor 1, is a single-chain protein containing 70 amino acids and three internal disulfide bonds. The Increlex prescribing information identifies mecasermin as recombinant human IGF-1 and describes IGF-1 as an important mediator of growth-hormone-dependent growth. Its biological actions include stimulation of tissue growth and effects on carbohydrate, lipid, and protein metabolism. The wording “IGF-1 Human” ordinarily points toward the human protein sequence, but a product specification is needed to distinguish native-sequence material from engineered analogues.

The European Medicines Agency describes Increlex as a medicine for growth failure associated with severe primary IGF-1 deficiency in children and adolescents. Its clinical assessment reports improved growth velocity in the studied population, providing human evidence for a defined recombinant medicine and indication. Research suppliers also use native human IGF-1 to investigate growth-factor signaling and cell responses. These contexts should remain separate: a human IGF-1 research vial is not identified solely by the clinical brand name, and neither DES truncation nor the LR3 extension should be inferred from the generic label.